Material Safety Data Sheet: Propyl Alcohol

Identification

Product Name: Propyl Alcohol
Synonyms: 1-Propanol, n-Propanol, Propan-1-ol
Chemical Formula: C3H8O
CAS Number: 71-23-8
Recommended Use: Solvent in manufacturing, pharmaceuticals, cleaning agents, antifreeze, and chemical synthesis
Manufacturer Contact: Name, address, and phone number required on official MSDS
Emergency Contact: Refer to local poison control/chemical emergency response numbers

Hazard Identification

Classification: Flammable liquid, eye irritant, harmful to respiratory system and central nervous system on overexposure
Hazard Statements: Highly flammable liquid and vapor, may cause drowsiness or dizziness, causes serious eye irritation, may be harmful if swallowed or inhaled
Precautionary Statements: Avoid breathing vapors, use in ventilated areas, keep away from heat and open flames, wear protective clothing and eye protection, wash hands thoroughly
Signal Word: Danger
GHS Label Elements: Flame symbol, exclamation mark symbol

Composition / Information on Ingredients

Chemical Name: 1-Propanol
Concentration: Typically ~99%
CAS Number: 71-23-8
Impurities: Trace water, trace amounts of higher alcohols depending on source

First Aid Measures

Inhalation: Move person to fresh air, keep quiet, seek medical help if symptoms persist, provide oxygen for difficult breathing
Skin Contact: Remove contaminated clothing, wash with soap and lukewarm water, medical attention for irritation
Eye Contact: Rinse eyes with water for 15 minutes holding eyelids open, remove contact lenses if easy, seek prompt medical advice
Ingestion: Rinse mouth, drink water if conscious, do not induce vomiting unless directed by medical personnel, call poison center or doctor
Most Important Symptoms: Headache, drowsiness, irritation, central nervous system depression with large dose

Fire-Fighting Measures

Extinguishing Media: Alcohol-resistant foam, dry chemical, CO2, water spray
Specific Hazards: Vapors can travel, can form explosive mixtures with air, emits toxic fumes including carbon monoxide
Protective Equipment: Firefighters use self-contained breathing apparatus and full protective gear
Advice for Firefighters: Cool containers with water, avoid runoff into drains, evacuate area if large fire threatens

Accidental Release Measures

Personal Precautions: Remove ignition sources, ventilate area, wear gloves, goggles, appropriate personal protection
Environmental Precautions: Prevent from entering soil, sewers, open water
Spill Response: Absorb with inert material like sand, collect in a container for disposal, wash spill area with water keeping run-off contained
Clean-Up: Dispose through regulated waste processor, ensure complete ventilation before re-occupying area

Handling and Storage

Handling: Work in well-ventilated spaces, avoid skin and eye contact, use spark-proof tools, ground containers before transfer
Storage: Store in tightly-closed, properly-labeled containers kept cool, away from heat, sparks, flames, oxidizers, and incompatible materials, secure against unauthorized access
Incompatibilities: Strong oxidizers, acids, bases, aluminum

Exposure Controls and Personal Protection

Exposure Limits: OSHA PEL 200 ppm (500 mg/m3), ACGIH TLV 100 ppm (246 mg/m3) for 8-hour TWA
Engineering Controls: Local exhaust ventilation, explosion-proof electrical fixtures, airflow monitoring
Personal Protective Equipment: Chemical safety goggles, gloves (nitrile or neoprene), apron, flame-resistant clothing in industrial settings, NIOSH-approved respirator for vapor
Hygiene Measures: Wash thoroughly after handling, change contaminated clothing, no smoking or eating in work area

Physical and Chemical Properties

Appearance: Clear, colorless liquid
Odor: Alcohol-like, slightly sweet
Odor Threshold: 10-50 ppm
Boiling Point: 97.2°C (207°F)
Melting Point: -126°C (-195°F)
Flash Point: 15°C (59°F) closed cup
Auto-ignition Temperature: 412°C (774°F)
Explosive Limits: 2.1% to 13.7% (by volume in air)
Vapor Pressure: 21 mmHg at 20°C
Relative Density: 0.803 g/cm3 at 20°C
Water Solubility: Miscible
pH: Not applicable (neutral in water)

Stability and Reactivity

Chemical Stability: Stable under normal temperatures and pressures
Reactivity: Reacts vigorously with strong oxidizers, forms explosive peroxide mixtures in air
Conditions to Avoid: Heat, open flames, sparks, static, incompatible materials, prolonged sunlight
Hazardous Decomposition: Releases carbon monoxide and dioxide under fire
Polymerization: Does not polymerize
Incompatible Materials: Strong acids, bases, oxidizers, aluminum, acid chlorides, acid anhydrides

Toxicological Information

Routes of Exposure: Inhalation, skin absorption, ingestion, eye contact
Acute Toxicity: Oral LD50 (rat) ~1870 mg/kg, Dermal LD50 (rabbit) ~4031 mg/kg
Effects: Irritation of eyes, skin, respiratory; headaches, dizziness, narcosis, depression of central nervous system
Chronic Exposure: Prolonged or repeated contact may cause dermatitis, possible liver or kidney damage at high exposures
Carcinogenicity: Not classified as carcinogen by OSHA, NTP, IARC
Sensitization: None recorded in reputable studies
Target Organs: Liver, kidneys, central nervous system

Ecological Information

Ecotoxicity: Toxic to fish and aquatic life at high concentrations, rapid degradation in environment
Persistence and Degradability: Rapidly biodegradable, low potential for bioaccumulation
Mobility in Soil: High mobility, readily mixes with water
Aquatic Toxicity: LC50 (fish, 96hr) ~4480 mg/L; EC50 (daphnia, 48hr) 3644 mg/L
Other Adverse Effects: High releases may contribute to oxygen depletion in water

Disposal Considerations

Waste Disposal Methods: Collect and store in labeled sealed containers, dispose through licensed chemical waste facility
Contaminated Packaging: Treat as hazardous waste, rinse and incinerate where allowed
Disposal Restrictions: Follow local, state, federal, and international regulations, do not allow into watercourses or sewers

Transport Information

UN Number: 1274
Proper Shipping Name: Propanol or Propyl Alcohol
Hazard Class: 3 (Flammable liquid)
Packing Group: II
Labels: Flammable liquid label
Special Precautions: Ensure caps are secure, stow away from heat, adjacent compartments should exclude oxidizers

Regulatory Information

US Regulations: SARA 313: Not listed, CERCLA: Not listed, OSHA: Flammable liquid
EPA TSCA: Listed
Canada DSL/NDSL: Listed
EU Regulations: Classified as flammable and irritating under Regulation (EC) No 1272/2008 (CLP)
Other Requirements: Ensure correct labeling, SDS available at all points of use, employer maintains worker training
Restrictions: No use by underage workers, do not use in food or drink products