Product Name: Nonylphenol
Chemical Formula: C15H24O
CAS Number: 25154-52-3
Synonyms: 4-Nonylphenol, para-Nonylphenol
Recommended Uses: Used in detergents, emulsifiers, plastics, pesticides, coatings, adhesives
Supplier Name and Contact: Manufacturer address and phone number provided on the container
Emergency Contact: 24-hour hazardous materials emergency hotline, CHEMTREC: 1-800-424-9300
Classification: Skin and eye irritant, toxic to aquatic life, possible endocrine disruptor
Signal Word: Danger
Hazard Statements: Causes serious eye and skin irritation, harmful if swallowed, long-lasting harmful effects to aquatic organisms
Pictograms: Corrosive, Environment, Exclamation Mark (as shown on container)
Precautionary Statements: Avoid skin and eye contact, do not breathe vapors or dust, keep out of waterways, wear proper PPE, avoid release into the environment
Chemical Name: Nonylphenol
Concentration: Pure grade (approx. 98%) in commercial products, trace impurities possible
Impurities: Alkylphenols (varied isomers), water & residual solvents less than 1% total
Ingredient List: No stabilizers or additives reported in basic commercial supply
Inhalation: Move exposed person to fresh air promptly, seek medical attention for breathing difficulty or persistent cough
Skin Contact: Remove contaminated clothing, wash exposed skin thoroughly with plenty of water and mild soap, medical help if irritation continues or chemical burns appear
Eye Contact: Rinse eyes immediately with clean water, lifting eyelids to flush thoroughly for at least 15 minutes, urgent medical attention if redness or pain persists
Ingestion: Rinse mouth, do not induce vomiting, seek immediate medical advice or transport to facility, show MSDS to physician if possible
Specific Notes: Symptomatic treatment supported by monitoring vital signs and supporting functions; safety showers and eyewash stations should remain close at hand in the workplace
Suitable Extinguishing Media: Dry chemical, foam, carbon dioxide, water spray (not stream), repel runoff
Unsuitable Extinguishing Media: Direct water jet may spread the chemical
Hazardous Combustion Products: Carbon monoxide, carbon dioxide, phenolic vapors, possibly irritating fumes
Advice for Firefighters: Wear self-contained breathing apparatus and flame-resistant protective gear, avoid inhalation of smoke or fumes, contain firefighting runoff to limit contamination of water sources
Fire and Explosion Risks: Moderate fire hazard, vapors heavier than air, can flow along surfaces and ignite from distant sources
Personal Precautions: Evacuate non-essential personnel, ventilate the area, avoid direct exposure to spilled material
Protective Equipment: Chemical-resistant gloves, splash goggles, coveralls, suitable respirator for vapor/dust
Environmental Precautions: Prevent spillage from reaching drains, sewers, or waterways, use absorbents like sand or vermiculite to control spread
Cleanup Methods: Contain spill, collect liquid in suitable containers for disposal, absorb residues, ventilate and wash contaminated slice, dispose of waste responsibly under hazardous materials rules
Handling: Use only with adequate ventilation, avoid splashing and spilling, keep away from sources of ignition, use local exhaust and properly sealed containers
Hygienic Practices: Do not eat, drink, or smoke while handling, wash hands and exposed skin thoroughly after contact
Storage Conditions: Store in tightly closed original containers in a cool, dry, well-ventilated space, away from food or incompatible materials like acids and oxidizers
Specific Storage Requirements: Clearly label storage area, maintain temperatures below 30°C, use corrosion-resistant shelving, segregate from reactive substances
Occupational Exposure Limits: No authoritative exposure limits set for nonylphenol, minimize exposures as low as possible
Engineering Controls: Use local and general exhaust ventilation to minimize airborne concentrations, install eyewash and showers nearby
Personal Protective Equipment (PPE): Provide chemical-resistant gloves (nitrile or butyl), full safety goggles, long-sleeve clothing or lab coats, respiratory protection for inadequate ventilation
Environmental Controls: Stop leaks and releases at the source, provide spill trays and secondary containment, regular monitoring for air and wastewater contamination
Appearance: Colorless or pale yellow viscous liquid
Odor: Mild, phenolic smell
pH: Not applicable (non-aqueous), but forms slightly acidic solutions in water
Boiling Point: 293°C (559°F)
Melting Point: –10°C (14°F)
Flash Point: 140°C (284°F)
Evaporation Rate: Slow
Solubility: Very slightly soluble in water, soluble in organic solvents (ethanol, ether, acetone)
Vapor Pressure: 0.1 mmHg at 20°C
Partition Coefficient (n-octanol/water): log Kow ≈ 4.48–5.76 (high potential for bioaccumulation)
Density: ~0.95 g/cm³ at 20°C
Viscosity: Moderately viscous at room temperature
Decomposition Temperature: Above 300°C
Explosion Limits: Not established
Auto-Ignition Temperature: >350°C
Chemical Stability: Stable at normal storage and handling conditions
Reactivity: Reacts with strong acids or oxidizing agents causing hazardous products; heats up under contact with bases
Hazardous Decomposition: On burning, releases toxic vapors, including phenolics and carbon oxides
Conditions to Avoid: Excess heat, open flames, incompatible chemicals
Incompatible Materials: Strong acids, oxidizers, some polymers, reducing agents
Polymerization: Not likely under regular use and storage conditions
Acute Toxicity (Oral): LD50 (rat) 580 mg/kg
Acute Toxicity (Dermal): LD50 (rabbit) 2031 mg/kg
Acute Toxicity (Inhalation): Data rare, but respiratory irritation reported
Skin Corrosion/Irritation: Causes moderate to severe irritation
Eye Damage/Irritation: Causes serious irritation, may result in corneal injury
Chronic Effects: Endocrine system disruption, reproductive toxicity, possible carcinogen in animal studies
Other Potential Effects: Prolonged skin exposure can cause sensitization, symptoms include redness, rash, burning sensation; ingestion leads to nausea, vomiting, abdominal pain
Aquatic Toxicity: Very toxic to fish and aquatic organisms, LC50 (fish) <0.1 mg/L, highly persistent in water and soil
Persistence and Degradability: Does not degrade quickly, known to bioaccumulate
Bioaccumulation Potential: High, as suggested by high log Kow
Mobility in Soil: Binds tightly to organic matter, slow groundwater movement
Other Adverse Effects: Disrupts hormone activity in wildlife, persistent in sediments and food chains, known for long-term environmental risk
Waste Treatment Methods: Dispose as hazardous waste in accordance with local, regional, national regulations, incineration under controlled conditions often used
Container Disposal: Rinse empty containers thoroughly, puncture before landfilling, return drums for professional recycling or destruction
Avoid: Direct discharge to waterways, landfills not equipped to handle hazardous organics
UN Number: 2810 (Toxic Liquid, Organic, N.O.S.)
Proper Shipping Name: Nonylphenol, Liquid
Transport Hazard Class: 6.1 (Toxic Substances)
Packing Group: III (Moderate hazard)
Environmental Hazards: Dangerous to the aquatic environment, marine pollutant
Special Transport Precautions: Keep containers upright and sealed, provide secondary containment, segregate from incompatible cargo
EU Regulations: Restricted under REACH, listed as Substance of Very High Concern (SVHC) for endocrine disruption
US Regulations: Listed on TSCA inventory, regulated under EPA’s Clean Water Act and Toxic Substances Control Act, subject to SARA 313 reporting
Canada: Regulated under CEPA, recognized as priority toxic
Other International Lists: Present in chemical inventories in Australia, China, Japan, Korea, subject to varied national restrictions and reporting duties
Labeling Requirements: Warning labels for environmental and health risks, accident prevention instructions, PPE recommendations displayed on packaging and storage tanks
