Material Safety Data Sheet: Isopropyl Alcohol

Identification

Product Name: Isopropyl Alcohol
Chemical Formula: C3H8O
Synonyms: 2-Propanol, Rubbing Alcohol, IPA
CAS Number: 67-63-0
Recommended Use: Solvent, Disinfectant, Cleaning Agent
Supplier Details: Include company name, address, phone number for emergencies
UN Number: 1219
Emergency Contact: Local poison control and emergency services phone

Hazard Identification

Classification: Highly flammable liquid, Category 2; Eye irritation, Category 2A; Specific target organ toxicity (single exposure), Category 3
Signal Word: Danger
Hazard Statements: Highly flammable liquid and vapor; causes serious eye irritation; may cause drowsiness or dizziness
Pictograms: Flame, Exclamation mark
Precautionary Statements: Keep away from heat, hot surfaces, sparks, open flames; no smoking; avoid breathing vapors; avoid contact with eyes; use protective equipment
Routes of Exposure: Inhalation, Skin, Eyes, Ingestion
Potential Health Effects: Eye irritation, headache, nausea, dizziness, respiratory tract irritation

Composition / Information on Ingredients

Component: Isopropyl Alcohol
Concentration: 99-100%
Chemical Name: Isopropanol
CAS Number: 67-63-0
Impurities: Trace amounts of water or denaturants in some grades
Additives: None in pure form

First Aid Measures

Inhalation: Move to fresh air; provide oxygen if breathing is difficult; seek medical attention if symptoms persist
Skin Contact: Remove contaminated clothing; wash with soap and water; seek medical advice if irritation develops
Eye Contact: Rinse cautiously with water for several minutes; remove contact lenses if present and easy to do; continue rinsing; seek immediate medical attention
Ingestion: Rinse mouth; do not induce vomiting; never give anything by mouth to an unconscious person; seek medical advice right away
Most Important Symptoms: Eye irritation, drowsiness, dizziness, headache, narcosis in severe cases
Immediate Medical Attention: Contact poison control or emergency medical services for large exposures or symptoms

Fire-Fighting Measures

Suitable Extinguishing Media: Alcohol-resistant foam, dry chemical, carbon dioxide
Unsuitable Extinguishing Media: Water jet, as it may spread fire
Specific Hazards: Vapors may travel and ignite at distant sources; highly flammable; forms explosive mixtures with air
Combustion Products: Carbon monoxide, carbon dioxide, acrid smoke
Protective Equipment for Firefighters: Self-contained breathing apparatus, full protective gear
Special Instructions: Cool containers with water spray to prevent rupture due to heat

Accidental Release Measures

Personal Precautions: Use protective equipment including gloves and goggles; ventilate area thoroughly
Environmental Precautions: Prevent entry into drains, sewers, water bodies
Methods for Containment: Stop leak if safe to do so; contain spill with inert materials such as sand or earth
Clean-Up Procedures: Absorb with non-combustible material; place containers for disposal; ventilate area and wash spill site after clean-up
Special Note: Small spills can evaporate quickly; large spills may require evacuation of area

Handling and Storage

Safe Handling: Use only in well-ventilated areas; keep away from sources of ignition; ground containers when transferring liquid
General Hygiene: Wash hands after handling; do not eat, drink, or smoke in use areas
Storage Conditions: Store in tightly closed containers in a cool, well-ventilated, and dry place; keep away from heat, sparks, open flames
Incompatible Materials: Strong oxidizers, acids, halogenated compounds
Storage Temperature Range: Keep below 30°C (86°F) for stability
Container Recommendations: Use containers made of compatible materials such as stainless steel or HDPE

Exposure Controls and Personal Protection

Exposure Limits: OSHA PEL: 400 ppm (980 mg/m3), ACGIH TLV: 200 ppm (TWA), 400 ppm (STEL)
Engineering Controls: Use ventilation systems to keep airborne concentrations below limits; consider explosion-proof equipment
Personal Protection: Chemical-resistant gloves (nitrile, neoprene); safety goggles or face shield for splash risk; flame-resistant clothing for handling large quantities
Respiratory Protection: Use approved respirator if ventilation is inadequate; for high vapor concentrations, supplied-air respirator recommended
Hygiene Measures: Avoid contact with skin and eyes; launder contaminated clothing before reuse

Physical and Chemical Properties

Appearance: Colorless, clear liquid
Odor: Alcohol-like, sharp
Odor Threshold: 22 ppm
Boiling Point: 82.5°C (180.5°F)
Melting Point: -89°C (-128°F)
Flash Point: 12°C (53.6°F)
Evaporation Rate: 1.5 (n-Butyl Acetate = 1)
Vapor Pressure: 33 mmHg @ 20°C
Vapor Density: 2.1 (air = 1)
Relative Density: 0.785 (water = 1)
Solubility: Miscible with water
Partition Coefficient: log P (octanol/water) = 0.05
Auto-ignition Temperature: 399°C (750°F)
Decomposition Temperature: No data
Viscosity: 2.43 mPa.s @ 20°C

Stability and Reactivity

Chemical Stability: Stable under recommended storage conditions
Reactivity: Highly flammable; reacts with strong oxidizing agents
Hazardous Reactions: May form explosive peroxides on prolonged exposure to air
Incompatible Materials: Halogens, strong acids, chromium trioxide
Decomposition Products: Burning produces carbon monoxide, carbon dioxide
Polymerization: Does not occur under normal conditions

Toxicological Information

Acute Toxicity: Oral LD50 (rat): 5,045 mg/kg; Dermal LD50 (rabbit): 12,800 mg/kg; Inhalation LC50 (rat, 4 h): 16,000 ppm
Short-Term Exposure Effects: Dizziness, headache, nausea, eye and respiratory irritation
Chronic Effects: Repeated exposure may cause skin dryness or cracking
Sensitization: Not classified as a sensitizer
Carcinogenicity: Not considered carcinogenic by IARC, NTP, OSHA
Mutagenicity: No data for mutagenic effects
Reproductive Toxicity: No evidence of reproductive toxicity in animal studies
Specific Target Organ Toxicity: Causes drowsiness and dizziness, especially in poorly ventilated conditions

Ecological Information

Ecotoxicity: Toxic to aquatic life in high concentrations; fish LC50 (96 h): ~9,640 mg/L (Pimephales promelas)
Persistence and Degradability: Rapidly biodegradable under aerobic conditions
Bioaccumulation Potential: Low, log P = 0.05
Mobility in Soil: High mobility; may leach into groundwater
Other Adverse Effects: Volatilizes rapidly from water and soil surfaces, reducing long-term environmental concerns; avoid large discharges to the environment

Disposal Considerations

Waste Treatment Methods: Incinerate under controlled conditions or send to a licensed chemical disposal facility
Disposal of Containers: Completely empty before recycling or disposal; puncture and triple rinse containers before discarding
Precautions: Do not pour into drains, soil, or waterways
Special Instructions: Consult local, regional, and national regulations; assign hazardous waste code D001 due to ignitability

Transport Information

UN Number: 1219
UN Proper Shipping Name: Isopropanol or Isopropyl Alcohol
Hazard Class: 3 (Flammable liquid)
Packing Group: II
Labels Required: Flammable liquid label
Transport in Bulk: According to Annex II of MARPOL 73/78 and IBC Code
Environmental Hazards: Not classified as marine pollutant
Special Precautions: Avoid transport with oxidizers, acids, alkalis; keep packages upright and sealed

Regulatory Information

OSHA: Hazardous under Hazard Communication Standard
TSCA: Listed on U.S. Toxic Substances Control Act inventory
SARA Title III: Listed under Section 311/312 (immediate, fire hazard); not subject to Section 313 reporting
CERCLA: Not listed
California Proposition 65: Not on Prop 65 list
Canada WHMIS: Classified as B2 (Flammable Liquid), D2B (Toxic Material)
International Inventories: Listed in EINECS, DSL, AICS, ENCS, and other chemical inventories
Other Requirements: Always check latest local, state, and international rules before transferring or disposing