Material Safety Data Sheet: Dipropylene Glycol Methyl Ether Acetate

1. Product Identification

Product Name: Dipropylene Glycol Methyl Ether Acetate
Synonyms: Propylene glycol methyl ether acetate, DPM Acetate
Chemical Family: Glycol Ethers
CAS Number: 88917-22-0
Recommended Use: Solvent for coatings, inks, cleaners, and industrial processes
Manufacturer: Typically large-scale chemical companies—check the container or accompanying paperwork for source details
Contact Information: Manufacturer telephone, emergency response number, and address listed in shipping documentation

2. Hazard Identification

Classification: Flammable liquid (Category 4), Eye irritant (Category 2A), Skin irritant (Category 2)
Signal Word: Warning
Hazard Statements: Causes serious eye and skin irritation, may cause respiratory discomfort, possible drowsiness, headache, or dizziness after exposure
Pictograms: Exclamation mark, flame
Precautionary Statements: Avoid breathing vapors, keep away from sparks, open flames, store in tightly closed containers, wash hands thoroughly after handling, wear protective gloves and goggles
OSHA Hazards: Mild narcotic effects at high concentrations, risk of fire in confined spaces

3. Composition / Information on Ingredients

Chemical Identity: Dipropylene Glycol Methyl Ether Acetate
CAS Number: 88917-22-0
Concentration: 100% pure or as listed on the label for mixtures
Impurities: Check supplier-specific documents for trace impurities below 1% noted in bulk chemical batches

4. First Aid Measures

Inhalation: Move to fresh air, rest, seek medical advice if symptoms persist (cough, dizziness, headache)
Skin Contact: Remove contaminated clothing, wash exposed area with soap and water, see a doctor for persistent irritation
Eye Contact: Rinse with plenty of clean water for at least 15 minutes, remove contact lenses if present, see a healthcare professional for redness or pain
Ingestion: Rinse mouth, do not induce vomiting, seek medical attention immediately, provide the chemical name to responders
Symptoms: Dizziness, nausea, irritation of eyes or skin, headache, possible coordination issues

5. Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, foam, carbon dioxide, dry chemical powder
Unsuitable Media: High-pressure water jets that could spread the substance
Specific Hazards: Vapors may form explosive mixtures with air in unventilated spaces, can produce toxic fumes of carbon monoxide or carbon dioxide when burned
Protective Equipment for Firefighters: Wear self-contained breathing apparatus, protective clothing, and stay upwind
Firefighting Measures: Cool exposed containers with water spray, evacuate area as needed, control runoff to prevent environmental contamination

6. Accidental Release Measures

Personal Precautions: Evacuate area for large spills, ventilate the spill site, wear gloves, splash goggles, and chemical-resistant clothing
Spill Containment: Stop leak if you can do so safely, block entry to sewers and drains, use dikes or absorbent materials (sand, inert clay, commercial absorbers)
Cleanup Method: Absorb liquid with inert material, scoop up and place in marked drum for disposal
Environmental Precautions: Prevent entry into ground water and waterways, notify authorities if contamination occurs

7. Handling and Storage

Handling: Use only in well-ventilated areas, avoid contact with skin and eyes, wear protective clothing, do not smoke or use open flames nearby, never eat or drink in work area
Storage: Store in closed, properly labeled containers away from heat or sources of ignition, keep storage area cool, dry, and well ventilated, keep incompatible materials like strong oxidizers away
Incompatibility: Store separate from acids, bases, and oxidizing agents, avoid storing with reactive metals

8. Exposure Controls and Personal Protection

Occupational Exposure Limits: ACGIH TLV/TWA: 50 ppm (manufacturer recommended)
Engineering Controls: Exhaust ventilation at work stations, fume hoods in labs, explosion-proof devices in flammable areas
Personal Protective Equipment: Chemical-resistant gloves (nitrile or neoprene), safety goggles, face shield for large splashes, flame-retardant lab coat, good shoes
Hygiene Measures: Wash hands after handling, change out of contaminated clothing, no food or beverages in the work area, shower at end of shift if heavily exposed

9. Physical and Chemical Properties

Appearance: Transparent, colorless liquid
Odor: Mild, ether-like, slightly sweet
pH: Not applicable (neutral chemical)
Melting Point: -66°C
Boiling Point: 190–210°C
Flash Point: 82°C (closed cup)
Vapor Pressure: 0.37 mmHg at 20°C
Density: 0.95–0.96 g/cm³
Solubility: Mixes well with water, most organic solvents
Auto-Ignition Temperature: About 300°C
Viscosity: Thin as compared to similar glycol ethers, easy to pour and pump
Evaporation Rate: Slower than many other ethers, so fewer vapors form at room temperature

10. Stability and Reactivity

Reactivity: Stable under recommended storage and handling conditions
Chemical Stability: Won't break down under normal temperatures or pressures
Hazardous Reactions: Doesn't react dangerously with common building materials, but strong oxidizers can cause fire or explosion
Decomposition Products: Combustion may generate toxic gases, especially carbon monoxide, in low-oxygen conditions
Polymerization: Will not self-polymerize

11. Toxicological Information

Routes of Exposure: Inhalation, skin contact, eye contact, ingestion
Acute Toxicity: Low acute toxicity by oral, dermal, or inhalation routes, but large doses can affect the central nervous system
Skin and Eye Irritation: Both are possible with direct exposure, not severely corrosive
Chronic Effects: No evidence of carcinogenicity, mutagenicity, or reproductive harm at standard exposure levels
Sensitization: Not known to cause allergic reactions after repeated use
Symptoms: Short-term headaches, mild dizziness, light skin or eye irritation, heavy or repeated exposure can worsen symptoms

12. Ecological Information

Ecotoxicity: Practically non-toxic to fish and aquatic life at low concentrations, contamination of waterways could be harmful in large spills
Persistence and Degradability: Breaks down slowly in water and soil, not likely to bioaccumulate
Mobility in Soil: Will move readily with water based on its solubility, runs risk of entering ground water if spilled
Bioaccumulation: Low potential, quickly processed by most organisms
Other Hazards: Large discharges may disrupt biological treatment processes at wastewater plants

13. Disposal Considerations

Disposal Methods: Incineration at approved facilities preferred, don't dump down drains or into the environment
Contaminated Packaging: Triple-rinse containers and send to approved drum recycler if possible
Waste Codes: Check local, state, and federal guidelines (EPA hazardous waste number D001 if ignitable, otherwise as a chemical waste)
Precautions: Never mix with incompatible chemicals when disposing, keep containers fully closed during handling

14. Transport Information

UN Number: UN 3272
Proper Shipping Name: Esters, N.O.S. (includes Dipropylene Glycol Methyl Ether Acetate)
Hazard Class: 3 (Flammable liquids)
Packing Group: III
Labels Required: Flammable liquid
Transport in Bulk: Use DOT-approved drums or ISO tanks, secondary containment for large shipments
Special Provisions: Make sure transport vehicles are ventilated and grounded; notify carriers about fire risks

15. Regulatory Information

OSHA: Considered hazardous under the OSHA Hazard Communication Standard
TSCA Status: Listed on the TSCA inventory
SARA Title III: May require reporting if threshold planning quantities exceeded in workplace
California Proposition 65: Not listed as causing cancer or reproductive harm
WHMIS (Canada): B3 (Combustible liquid with serious eye and skin effects)
Other International Regulations: Registered under REACH (Europe), has GHS classification matching U.S. standards