Dipropylene Glycol Methyl Ether Acetate—often seen on supply sheets as DPM Acetate or among chemists as DPMAc—roots itself deep in the development of slow-evaporating solvents for coatings and industrial cleaning. People tracked through the march of the 20th century with a constant need for solvents that blended power, mildness, and versatility. Multinational chemical giants, including Dow Chemical, played a role in pioneering ether acetates for specialty coatings and inks, so DPMAc grew from a desire to push past the limitations that purely aromatic or hydrocarbon-based solvents kept creating, especially as environmental and worker safety awareness began shifting policies worldwide. Watching how certain chemicals morphed from basic industrial utility to regulatory headaches provides some insight: DPMAc hung onto its niche by combining stability and moderate toxicity with good solvency.
DPMAc usually rolls out as a colorless, almost odorless liquid, showing up in the corner of paint shops, print shops, and electronics assembly benches. Companies order it by the drum for reformulating lacquers and as a staple in cleaning fluids. Unlike some aggressive solvents, DPMAc tends to be kinder to both old paint work and newer eco-friendly finishes. Its real edge: strong solvency without chewing up safety margins as fast as some low-boiling ethers or ketones. The stuff costs a bit more than basic acetone or xylene, but the results in fewer ruined batches and more predictable finish work mean buyers keep calling for it.
With a molecular formula of C8H16O4 and a molar mass a few grams over 176, DPMAc doesn’t bring the heavy punch of some classic industrial nasties. Its boiling point sits comfortably around 190°C, making it less prone to vapor emissions in warm workrooms. The density hovers near 0.96 g/cm³, and it mixes well with most ether and ester solvents. Flash point sits at a reassuring 75°C—safe enough for careful handling but never loose enough to ignore good practice. Low vapor pressure means better air quality, which matters in spaces where workers want to finish shifts headache-free.
On any technical data sheet, DPMAc goes by more than just one name. Look for ‘Dipropylene glycol monomethyl ether acetate’ or ‘Propylene glycol methyl ether acetate’—differences often signal grades or blends. Purity runs over 98 percent for most commercial blends, water content must fall well below 0.05 percent, and color usually sits under 10 on the APHA scale. Labels should clearly state the CAS number (88917-22-0, or mixes under 1320-67-8) since close relatives exist and accidental swaps cause trouble fast during formulation. Look for careful documentation on shelf life and storage—most suppliers recommend steel drums in well-ventilated areas, away from strong acids or bases.
Producers start by reacting propylene oxide with methanol, running the resulting glycol through an acetylation process using acetic anhydride or acetic acid in the presence of a catalyst. This reaction brings efficiency, but reaction conditions must stay tightly controlled; overcooking yields unwanted byproducts, while sloppy monitoring drops yield and purity. I’ve watched plant operators juggle tank temperatures and flow meters—small errors multiply fast. Scaling things up for industry means search for catalysts, reaction vessels, and energy sources that keep output steady without letting contamination step in.
DPMAc acts as a stable solvent but won’t stay inert when mixed into certain systems. Under acidic or basic conditions, especially at higher temperatures, hydrolysis can slowly chip away at the molecule to spit out dipropylene glycol, methanol, and acetic acid. In practical terms, this limits certain aggressive paint stripper or cleaner blends: too high a pH and DPMAc doesn’t last the work shift. On the upside, its low reactivity keeps it compatible across most standard resins, including acrylics, polyurethanes, and epoxies, letting formulators tune evaporation rates and flow without risking unwanted gelling or premature curing.
Depending on the manufacturer or the region, DPMAc sails under a mix of aliases. Look for ‘Arcosolv PMA’, ‘Propasol P’, ‘Dowanol DPMA’, and sometimes just ‘Glycol ether PMAc’. These names confuse new buyers, who often don’t know if they’re ordering the same thing as their production partner on the other side of the border. Standardizing naming conventions saves supply chain headaches; in my own work, checking CAS numbers sidesteps vendor mislabeling.
Safe handling for DPMAc relies on good workplace habits. Safety Data Sheets highlight irritation risks—prolonged skin exposure can cause dryness and redness, inhalation of high vapor concentrations leads to drowsiness or mild respiratory effects, but acute danger levels remain lower than with faster-evaporating glycol ethers. Workers wear gloves and goggles, and ventilation takes center stage. Storage regulations call for flame-tight containers, separate from oxidizing agents. Spill response means absorbing with inert material and cleaning with plenty of fresh air around. Disposal channels follow local environmental rules, especially since ethers linger in groundwater unless handled with proper waste collection.
The world uses DPMAc for more than just paint and cleaning. In my corner of industrial tech, it’s a favorite as a carrier for dyes and pesticides, where it helps dissolve actives that resist water alone. Electronics manufacturing draws on DPMAc for flux removal and delicate surface prep. Printing ink formulations take advantage of its moderate evaporation time and its ability to keep pigment slurries from settling too fast or drying too slow. It even pops up in adhesives—enabling hard-to-bond plastics and composites to stay tacky long enough for precise assembly.
Labs still dig deep into DPMAc’s solubility landscapes, tracking how this ether acetate boosts performance in low-VOC coatings and novel pigment dispersions. Teams test new blends to lower odor and further cut worker risk, especially in tight, recirculated work cells. Pilot projects keep probing for greener raw materials—bio-based glycols and recycled acetic acid streams—to meet shifting sustainability standards. Researchers pay attention to molecular tweaks that hold solvent power steady while shrinking environmental footprint, since upcoming regulations push every formulator to justify every ingredient on an environmental, safety, and health basis.
Study after study puts DPMAc in the low-to-moderate hazard category. Acute oral and dermal tests in lab animals run at high doses to trigger significant effects—real-world exposure rarely comes close in responsible workplaces. Long-term exposure, though, still stirs concerns for reproductive and developmental outcomes based on tests at high concentrations. Environmental fate hinges on relatively slow biodegradation once the molecule hits wastewater, creating a push for pre-treatment and recycling. OSHA and the EU keep updating workplace exposure limits; awareness grows steadily among workers and managers as better monitoring tools roll out.
Looking further down the pipeline, DPMAc’s future depends on how coatings and cleaning industries balance regulatory pressure with a need for solvents that don’t wreck productivity. Smarter engineering could soon yield even lower-emission blends, with chemical manufacturers eyeing next-generation glycol ethers based on renewable or circular feedstocks. Digital supply chains and AI-powered lab work support rapid prototyping of new solvent systems, aided by ongoing life-cycle analyses to weigh performance against full-cost environmental impacts. The trend pulls toward solvents that can deliver indoor air quality improvements, more predictable work cycles, and easier end-of-life treatment—all without forcing a split between chemical reliability and safer, cleaner production floors.
My first run-in with industrial chemicals didn’t come from a factory tour or a science class, but from working at an auto body shop. All those shiny painted surfaces, the solvents, the days scrubbing paint off my hands—turns out, Dipropylene Glycol Methyl Ether Acetate, or DPM Acetate for short, plays a big part in a job like that. Most people never give it much thought, but this stuff turns up everywhere, right down to the products on your desk.
Painters who want even coats and glossy finishes lean on DPM Acetate to get there. It slows down drying times, so no one has to rush the brush and panic over weird streaks or lumps. Furniture makers, automotive shops, and even folks renovating their kitchens count on this solvent. Without it, paints would turn sticky or bubble up before anyone could finish their work. That means fewer costly do-overs and less waste—in workshops, every wasted can hits profit margins hard.
Most cleaning crews dread using harsh solvents because of the heavy fumes and cracked skin that follow. DPM Acetate steps in here, too. Its mild smell and gentle touch on skin don’t send workers running for fresh air after ten minutes. In my stint cleaning printing presses, strong cleaners caused daily headaches, but formulas using DPM Acetate tasted less like poison in the air. Data from occupational health groups back this up; exposure limits for DPM Acetate run less strict than for stronger cousins like toluene or acetone. That smoother safety record helps keep long-term health complaints down.
Modern tech runs on tiny, precise parts. Factories making circuit boards or hard drives count on solvents that won’t eat through metal or plastic. DPM Acetate fits in just fine. Its slow evaporation rate suits carefully timed production lines. Printers using specialty inks appreciate how consistently it acts. I know printers who switched to DPM Acetate-based solutions after years of fighting clogs and dried ink. The stories are always the same: smoother print runs, happier techs, and fewer maintenance calls.
Painters, print shops, and even electronics manufacturers care about what happens to the air in their buildings and what’s left over at the end of a shift. Moving away from the harshest solvents is a small step, but it matters over years and across industries. DPM Acetate isn’t perfect. In high doses, it still causes problems. But each time a shop trades up to a safer, better-balanced solvent, it means workers breathe easier and the environmental load ticks down a notch. Substitution gets easier as more research points out health-friendly mixtures and better ventilation strategies.
I’ve seen people get sick from ignoring safety sheets and cutting corners. Small changes—like picking a solvent with a softer edge—mean fewer risks and a stronger argument for modernizing old practices. That push for safer, more reliable tools doesn’t just protect workers now. It opens the door to smarter, more responsible manufacturing down the road, and DPM Acetate stands as a sign of how habits can improve when enough people care.
You don't need to work in a chemical plant to realize that some industrial solvents do more harm than help. Every few years, a long-name ingredient in paints, inks, or cleaners gets into the spotlight and scares people who can barely pronounce it. Today, Dipropylene Glycol Methyl Ether Acetate, or DPM Acetate, gets that look. This isn’t some mystical chemical dreamt up in a lab; it's a workhorse. Factories love it because it dissolves things and dries slow enough for smooth finishes. But just because it gets the job done doesn't mean it's completely safe.
Ask anyone who’s ever worked on a factory floor—opening drums with this stuff inside calls for respect. Breathing the fumes too long, especially without fresh air, can burn your nose and throat and sometimes gives you a headache. Touching it with bare hands for a while often dries out your skin and even causes irritation. Several health agencies, including OSHA, set guidelines for how much vapor is allowed in workspaces, and those rules don’t come out of nowhere.
One thing I remember from my early shop days is how easy it is to shrug off minor irritations. A few sniffles, a bit of red skin, and people power through. But studies show that repeated overexposure raises the risk for more severe effects, like nervous system troubles or liver stress. Some workers ended up with confusion and dizziness after spending eight-hour shifts around high vapor concentrations. This isn’t about scaring people with chemistry; it’s about respecting the stuff that goes into products we use.
No one’s arguing DPM Acetate is as dangerous as, say, benzene or toluene, which have long histories of wrecking people’s health. This solvent doesn’t build up in your body the way mercury or lead does. Still, if you swallow a mouthful, you’ll probably land in the hospital. The good news: most reported accidents involve careless handling, not just everyday use in a ventilated workspace.
A common myth claims consumer products are always safe if they’re on a store shelf. I don’t buy it. DPM Acetate can sneak into homes through paint thinners or specialty cleaners. At home, people rarely use gloves or work in well-aired rooms. Kids or pets can get curious, and a little spill sometimes becomes a serious problem if it’s not cleaned up right away.
We have the information to do better than before. Manufacturers keep working to cut back on harsh solvents or swap them out for safer substitutes where possible. Not every substitute is perfect—some are a pain to work with or cost way more. Still, there’s no sense ignoring alternatives just because the old way seems easier or cheaper for the short term.
For workers and anyone else who gets near DPM Acetate, wearing gloves, using good ventilation, and keeping containers closed make a real difference. Even small changes on the job floor or at home beat down most of the risk. I’ve seen more companies make regular safety training a must, not just a box to tick. With EPA regulations getting tighter, ignoring warnings bites back harder than ever.
No chemical offers pure convenience with zero risk. Dipropylene Glycol Methyl Ether Acetate stands out as a fair choice for certain uses, if folks give it the respect it has earned. Safety isn’t a luxury for someone else—it comes down to decent habits and making smart choices every day.
Working in places where chemicals are stacked on shelves or moved in drums brings its own set of headaches and worries. Nobody forgets the time a leaky cap started a rush to the eyewash station, or the strong smell slipping under the storeroom door. People often talk about regulations and manuals, but what matters most is paying attention and sticking to simple habits that keep the workspace safe.
Many chemicals demand specific storage conditions, not because policy says so, but because a careless moment can cost real money, time, and health. Take strong acids: glass bottles work for some, but others chew through plastic or metal in weeks. I've seen coworkers grab the wrong jar, only to see their gloves start bubbling halfway through a task. Labels fade, containers crack, humidity sneaks into lids, and next thing you know, a harmless-looking powder turns into a problem overnight.
Temperature swings deserve special attention, especially for volatile solvents. On a hot day, those vapors quickly build up—sometimes past the flash point before anybody smells a thing. I remember one summer when an overloaded storage closet with poor airflow turned into a small disaster. No fancy warning; just the sharp sting of burnt plastic and a lesson learned about never blocking the vent because it “looked ugly.”
Moving chemicals safely is more than checking off a task on a clipboard. Each transfer, pour, or mix brings risk. Some comrades in my field skipped the splash goggles just once—and that mistake cut their day short. Proper gear isn’t a suggestion; it’s the difference between going home safe and filling out accident forms. Researchers at the National Safety Council point out that chemical-related injuries account for thousands of lost work days every year—simple steps like double-checking seals or storing bottles at eye-level prevent spills and injuries more often than fancy containment equipment.
Spills happen, no matter how carefully you plan. I’ve seen a colleague use kitty litter and neutralizers more than once to tackle a slippery floor. But the real skill comes in having clear instructions near the entry—nobody wants to flip through a binder while fumes are filling the room. One effective practice is color-coded bins for acid, base, or solvent cleanups, along with gloves in every room, not just the hazardous waste closet. It’s all about removing hesitation.
Routine inspections sound boring, but I can count at least four times when one quick glance found a cracked lid or corrosion around a valve. Those problems left alone might have led to expensive shutdowns or worse. Grouping chemicals by compatibility, not just alphabetically, keeps things tidy and also stops surprise reactions from stray drips. Every storage area should have a spill kit, an eye wash, and space to work. I’ve seen leadership try to tick off safety checklists, but only regular talks with frontline workers lead to improvements in both storage and handling.
If there’s one thing experience has taught me, it’s that you can't rush safety—every shortcut carries a cost, and a bit of planning today keeps tomorrow free from drama.
Dipropylene Glycol Methyl Ether Acetate, known in the chemical industry by its formula C10H20O4, often goes by the shortened name DPM Acetate. Some chemists and manufacturers track it through its CAS number, which is 88917-22-0. Simple numbers, but they open the door to a whole world of practical knowledge.
Plenty of us just hear these complex names and want to shrug them off as industry jargon. Figuring out what a substance like DPM Acetate actually does, and why its formula even matters, brings us closer to safer workspaces and solid products. Behind those numbers and letters hides a lot of real-world impact—something I learned the first time I talked with a safety officer who had to run down a spill at a warehouse. He didn’t need a general overview—he needed precise details.
Mislabeling or confusing chemical compounds has direct effects you feel right away. Factories use DPM Acetate in paints, inks, and cleaning agents. Mislabelling could risk ruined batches or even personal harm. In my experience talking with coatings professionals, the right formula means the difference between a product that holds up on a rainy day and paint that peels after a week.
Simple slip-ups make headlines. Campus science labs, large-scale manufacturers, and even artisans working from home all depend on pinpointing the correct CAS number. Once, a colleague told me about a batch of industrial cleaner that showed unexpected corrosion. After a few days of head-scratching, they traced it to the wrong glycol ether variant. The right label would have avoided both lost time and equipment damage.
Those working with Dipropylene Glycol Methyl Ether Acetate count on that formula—C10H20O4—because each atom sets its properties. With this mix, it balances solvent power against gentle evaporation. You want a solvent that won’t make you run out of air, but that still gets the job done without gumming up the works. Paint shops reach for DPM Acetate when they need slow, even drying, especially in water-based blends where consistency is key. SVOCs like this have become popular in big facilities for good reason: less odor, less hazard, and more control.
Spend enough time in a production plant and you learn that clear labels mean fewer close calls. Listing the right chemical formula or CAS number shuts down both guesswork and shortcuts. Suppliers often highlight a product’s formula on their shipping labels. This isn’t just bureaucracy; it helps firefighters, warehouse staff, and environmental crews know what they’re dealing with in case of leaks or fires.
Easy solutions start with double-checking every drum and bottle for its CAS number—88917-22-0 in this case. Regular training around these exact codes pays off. Some workplaces tape laminated sheets inside supply rooms showing common solvents and their formulas. It isn’t fancy, but people spot a mismatch quickly.
Surveys from safety groups show drops in chemical accidents where the workers take fifteen seconds to check those numbers before use. Real habits, not paperwork, improve outcomes. Tough as it sounds, this attention to detail grows over time with the right culture.
Chemical numbers might look like background noise, but they matter where rubber meets the road. Whenever I’ve met hands-on operators, they trust those codes to keep their teams steady. By focusing on details like the formula or CAS number, users keep risks low, quality high, and work running without surprises. In the end, good habits around chemical information help everyone—from the crew on the line to folks dealing with cleanup months later.
Spilling chemicals in a workspace never feels routine, even in industries where solvents like Dipropylene Glycol Methyl Ether Acetate play a regular role. The clear liquid doesn’t bring about immediate panic the way some hazardous acids or reactive agents do, but that’s how complacency gets a foothold. I’ve seen cleanup crews get lax around it, but when you spend enough time in labs or on paint-shop floors, you remember that even “safer” solvents demand respect.
One key problem with Dipropylene Glycol Methyl Ether Acetate isn’t some dramatic reaction; it’s the slow, persistent exposure to vapors or skin contact. You won’t see skin melt or cough uncontrollably, but headaches, dizziness, or eye irritation tell you something is wrong. Over weeks, toxic levels add up. OSHA tags this chemical as an irritant, and animal studies have shown organ damage after long exposure. Workers who get casual about PPE risk ending up sicker than they expect.
Immediate response is simple: stop, contain, clean. I’ve handled my share of spills on concrete and linoleum. Stop the spread by blocking the liquid with absorbent pads or sand. No one races for the mop before gloving up and grabbing goggles. Even on a “small” spill, solvent-proof gloves, splash goggles, lab coat, and good ventilation make sure the person doing cleanup stays out of harm’s way.
Dry materials, not wet towels, pull up chemical puddles safely. Double-bag waste, seal it, and label the bag—no shortcuts. I’ve seen janitors dump used rags in open bins, and the room starts to smell hours later. Fumes don’t warn you with big clouds, but anyone walking through catches a breath, and headache or nausea follows.
Lousy air circulation turns a minor spill into a building-wide issue. Fans help; a good fume hood is even better. Facilities skimp on steady ventilation, telling workers to just “open a window,” but one spill in a basement workspace proves that’s not enough. Some companies now set up fixed exhaust lines near work tables. Building teams get sick of calls, so fresh air stops being a second thought.
Chemical training days, back in my old lab, never focused on glossy handouts or endless slideshows. The good trainers dragged in buckets, gloves, and actual product, then staged fake spills. That sticks with people. No one prefers theory to practice once they smell the solvent or see it soak into pant cuffs. Departments that rotate safety reviews, keep written instructions near cleanup kits, and check date stamps on spill-response supplies keep accidents from turning into long-term health messes.
Label all bottles, not just main drums. Lock up storage after hours. Make eyewash stations and showers easy to reach—not blocked by boxes. Old pipes or crumbling floors need more than duct tape and hope: catch leaks before they become “normal.” Small investments in safety gear and ongoing training save money on sick days, worker’s comp, and lost trust. That’s the kind of bottom line I’ve seen actually matter.
Names | |
Preferred IUPAC name | 1-(2-Methoxy-1-methylethoxy)propan-2-yl acetate |
Other names |
DPMA 1-(2-Methoxy-1-methylethoxy)-2-propanol acetate Propylene glycol methyl ether acetate Dipropylene glycol monomethyl ether acetate |
Pronunciation | /daɪˌprəʊpiːliːn ˈɡlaɪˌkəʊl ˈmɛθəl ˈiːθər əkˈsɪteɪt/ |
Identifiers | |
CAS Number | 88917-22-0 |
Beilstein Reference | 3118736 |
ChEBI | CHEBI:89217 |
ChEMBL | CHEMBL1651948 |
ChemSpider | 12088 |
DrugBank | DB14006 |
ECHA InfoCard | 03e7c1c1-8f2b-4305-95b6-1367951b6f54 |
EC Number | wtih EC Number 252-091-3 |
Gmelin Reference | 102149 |
KEGG | C14319 |
MeSH | D004083 |
PubChem CID | 8186 |
RTECS number | JM1575000 |
UNII | 7W6A9E754U |
UN number | UN3272 |
CompTox Dashboard (EPA) | DPGMA |
Properties | |
Chemical formula | C10H20O4 |
Molar mass | 190.24 g/mol |
Appearance | Clear, colorless liquid |
Odor | Mild, ester-like |
Density | 0.951 g/cm³ |
Solubility in water | Miscible |
log P | 0.36 |
Vapor pressure | 0.05 mmHg @ 20°C |
Acidity (pKa) | pKa ≈ 14.8 (estimated) |
Basicity (pKb) | 7.91 |
Magnetic susceptibility (χ) | -7.89×10⁻⁶ cm³/mol |
Refractive index (nD) | 1.406 |
Viscosity | 0.95 mPa·s |
Dipole moment | 1.85 D |
Thermochemistry | |
Std molar entropy (S⦵298) | 309.3 J·mol⁻¹·K⁻¹ |
Std enthalpy of formation (ΔfH⦵298) | -675.4 kJ/mol |
Std enthalpy of combustion (ΔcH⦵298) | -4175 kJ/mol |
Pharmacology | |
ATC code | D01AE23 |
Hazards | |
GHS labelling | GHS02, GHS07 |
Pictograms | GHS02, GHS07 |
Signal word | Warning |
Hazard statements | H226, H336 |
Precautionary statements | P210, P233, P240, P241, P242, P243, P261, P271, P280, P303+P361+P353, P305+P351+P338, P337+P313, P370+P378, P403+P235, P501 |
NFPA 704 (fire diamond) | 1-2-0 |
Flash point | > 75°C (167°F) |
Autoignition temperature | 180°C |
Explosive limits | 1.1% - 8.5% |
Lethal dose or concentration | LD50 (oral, rat): 5,192 mg/kg |
LD50 (median dose) | 6500 mg/kg (rat, oral) |
NIOSH | WVQN000042 |
PEL (Permissible) | 50 ppm (TWA) |
REL (Recommended) | 15 ppm |
Related compounds | |
Related compounds |
Dipropylene glycol methyl ether Propylene glycol methyl ether acetate Ethylene glycol methyl ether acetate Propylene glycol n-butyl ether Dipropylene glycol dimethyl ether |